Insulin-like growth factor-I (IGF-I) is essential for normal epidermal homeostasis; however, the role of IGF binding proteins (IGFBPs), regulators of IGF action, remains unclear. Here we examine the regulation of human keratinocyte-produced IGFBPs by epidermal growth factor (EGF), transforming growt
✦ LIBER ✦
EGF-like factor epiregulin and amphiregulin expression is regulated by gonadotropins/cAMP in human ovarian follicular cells
✍ Scribed by S. Freimann; I. Ben-Ami; A. Dantes; R. Ron-El; A. Amsterdam
- Book ID
- 116289274
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 473 KB
- Volume
- 324
- Category
- Article
- ISSN
- 0006-291X
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## Abstract The net balance between urokinase‐type plasminogen activator (uPA) and plasminogen activator inhibitor type‐1 (PAI‐1) has been implicated in tumor cell invasion and metastasis. To elucidate the mechanism of the transforming growth factor‐β1 (TGF‐β1)‐dependent up‐regulation of PAI‐1 expr