EGF and β1 Integrin Convergently Regulate Migration of A431 Carcinoma Cell through MAP Kinase Activation
✍ Scribed by Ei Kawahara; Natsuko Nakada; Tetsuro Hikichi; Jun Kobayashi; Isao Nakanishi
- Book ID
- 115604162
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 270 KB
- Volume
- 272
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Maintenance of β1 integrin‐mediated cell adhesion in quiescent human mammary epithelial (HME) cells requires protein phosphatase (PP) 2A for not only dephosphorylation of β1 integrin but also recruitment of IQGAP1 to Rac‐bound β1 integrin. However, how PP2A‐dependent regulatory machiner
HeLa cell spreading on a gelatin substrate requires the activation of protein kinase C (PKC), which occurs as a result of cell-attachment-induced activation of phospholipase A2 (PLA2) to produce arachidonic acid (AA) and metabolism of AA by lipoxyginase (LOX). The present study examines how PKC acti