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EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast

✍ Scribed by Cai, Yi; Yu, Shan-Shan; Chen, Ting-Ting; Gao, Si; Geng, Biao; Yu, Yang; Ye, Jian-Tao; Liu, Pei-Qing


Book ID
122396294
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
899 KB
Volume
20
Category
Article
ISSN
0944-7113

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Interleukin-18 stimulates fibronectin ex
✍ Venkatapuram Seenu Reddy; Ralf Egan Harskamp; Margreet Willie van Ginkel; John C 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB

## Abstract Fibronectin (FN), a key component of the extracellular matrix, is upregulated in cardiac tissue during myocardial hypertrophy and failure. Here we show that interleukin (IL)‐18, a proinflammatory and pro‐hypertrophic cytokine, stimulates FN expression in adult human cardiac fibroblasts