Blood–brain barrier efflux transport
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Pamela L. Golden; Gary M. Pollack
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Article
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2003
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John Wiley and Sons
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English
⚖ 193 KB
Efflux transport at the blood-brain barrier (BBB) limits the brain tissue exposure to a variety of potential therapeutic agents, including compounds that are relatively lipophilic and would be predicted to permeate the endothelial lining of the brain microvasculature. Recent advances in molecular an