Efficient Two-Step Conversion of α,β-Unsaturated Aldehydes to Optically Active γ-Oxy-α,β-unsaturated Nitriles and Its Application to the Total Synthesis of (+)-Patulolide C
✍ Scribed by Tian, Jun; Yamagiwa, Noriyuki; Matsunaga, Shigeki; Shibasaki, Masakatsu
- Book ID
- 126184919
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 87 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
Diphenyl cyanomethylenephosphonate (PhO)2POCH2CN was prepared as a stable crystalline solid in high yield in a single step from acetonitrile, LDA, and (PhO)2P(O)C1. The potassium ylide generated from this compound afforded o;//-unsaturated nitriles upon reacting with aldehydes, with a stereoselectiv
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