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Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation–ring-opening of cyclopropane–intramolecular cyclization

✍ Scribed by Liang, Fushun; Cheng, Xin; Liu, Jing; Liu, Qun


Book ID
120663850
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
524 KB
Volume
24
Category
Article
ISSN
1359-7345

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## Abstract The hitherto unreported, highly functionalized 1__H__‐pyrazole‐3‐carboxylates **3** have been synthesized in good yields __via__ a one‐pot three‐component domino reaction of phenylhydrazines, dialkyl acetylenedicarboxylates, and ninhydrin under mild conditions for the first time. No co‐