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✦ LIBER ✦
Efficient synthesis of syn-aziridino alcohols by chelation-controlled addition of dialkylzincs and Grignard reagents to N-benzylaziridino aldehydes
✍ Scribed by JoséM. Andrés; Noemí de Elena; Rafael Pedrosa; Alfonso Pérez-Encabo
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 450 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
✦ Synopsis
N-Benzyl aziridino aldehydes, derived from (l.)-seaine and fL)-~ react with dialkylzinc and alkyimagnesium halides leading to syn-aziridino alcohols as single or major stereoisomers. The diaslexeoselec tivity is affe, eted by the nature of the organometallic and the solvent system.
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