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Efficient synthesis of syn-aziridino alcohols by chelation-controlled addition of dialkylzincs and Grignard reagents to N-benzylaziridino aldehydes

✍ Scribed by JoséM. Andrés; Noemí de Elena; Rafael Pedrosa; Alfonso Pérez-Encabo


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
450 KB
Volume
55
Category
Article
ISSN
0040-4020

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✦ Synopsis


N-Benzyl aziridino aldehydes, derived from (l.)-seaine and fL)-~ react with dialkylzinc and alkyimagnesium halides leading to syn-aziridino alcohols as single or major stereoisomers. The diaslexeoselec tivity is affe, eted by the nature of the organometallic and the solvent system.


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ChemInform Abstract: Efficient Synthesis
✍ Jose M. Andres; Noemi de Elena; Rafael Pedrosa; Alfonso Perez-Encabo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

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