Efficient synthesis of purines by inverse electron-demand Diels–Alder reactions of 1-substituted-1H-imidazol-5-amines with 1,3,5-triazines
✍ Scribed by Viktor O. Iaroshenko; Aneela Maalik; Dmytro Ostrovskyi; Alexander Villinger; Anke Spannenberg; Peter Langer
- Book ID
- 113928903
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 624 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Intermolecular cycloadditions between trialkyl 1,2,4-triazine-4,5,6-tricarboxyIatesand protected2-aminoimidazolegave IH-imidazo[4,5-c]pyridines (3-deazapurines)andthe rearranged3Hpyrido[3,2-d]pyrimid-4-ones (8-deazapteridines). No cycloadditions wereobservedwithimidazoleand2phenylimidazole.Q 1997Els
Imidazole and 2-phenylimidazoleundergo intramolecularcycloadditions with 1,2,4triazines tethered betweenan imidazolenitrogenand the triazinylC3 position with a trimethylene chainto producetetrahydro-l,5-naphthyridines followingloss of N2 and a nitrile.