Efficient synthesis of novel thieno[3,2-b]-, [2,3-c]- and [3,2-c]pyridones by Sonogashira coupling of bromothiophenes with terminal alkynes and subsequent intramolecular C–N bond-forming reaction
✍ Scribed by Iaroshenko, Viktor O.; Ali, Sajid; Babar, Tariq Mahmood; Abbasi, Muhammad S.A.; Sosnovskikh, Vyacheslav Ya; Villinger, Alexander; Tolmachev, Andrey; Langer, Peter
- Book ID
- 120008185
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 596 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Alkylation of 1,2,4-triazine-6-thiones with 4-iodobutyne, followed by oxidation to the sulfoxide and intramolecular cycloaddition (at room temperature), gives 2,3-dihydrothieno[2,3-c]pyridines, which are readily dehydrated with acetic anhydride to thieno[2,3\_c]pyridines. The same series of reactio
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