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Efficient synthesis of new 5-substituted uracil nucleosides useful for linker arm incorporation

✍ Scribed by Sawai, Hiroaki; Nakamura, Akiko; Sekiguchi, Sumie; Yumoto, Keisuke; Endoh, Masakazu; Ozaki, Hiroaki


Book ID
117992160
Publisher
The Royal Society of Chemistry
Year
1994
Tongue
English
Weight
251 KB
Volume
17
Category
Article
ISSN
0022-4936

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A new convenient synthesis of 5-aryl ura
✍ Maurice MΓ©debielle; Mehmet Ali Oturan; Jean Pinson; Jean-Michel SavΓ©ant πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 French βš– 266 KB

Direct and indirect electrochemical reduction of aryl halides in the presence of the uracil anion in dimethylsulfoxide yields the corrsponding S-aryl uracils by an SRNI mechanism. Nucleophilic aromatic substitution catalyzed by electron injection (electrochemical, photochemical, solvated electrons,