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Efficient synthesis of N-substituted lactams from (N-arylsulfonyloxy) amines and cyclic ketones

โœ Scribed by Robert V. Hoffman; James M. Salvador

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
276 KB
Volume
30
Category
Article
ISSN
0040-4039

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A mild, convenient, and practical one-pot procedure for direct synthesis of N,N 0 -dialkyl-N 00 -dialkylaminocarbothioyl thioureas is described via three-component reaction of cyclic secondary amines, CS 2 , and N,N 0 -dialkyl carbodiimides in water at room temperature.