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Efficient synthesis of jusbetonin, an indolo[3,2-b]quinoline glycoside, and its derivatives

โœ Scribed by Zhongwei Zhang; Shixi Wang; Shengbiao Wan; Sumei Ren; Wei Li; Tao Jiang


Book ID
108080595
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
214 KB
Volume
344
Category
Article
ISSN
0008-6215

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A new and a more efficient synthesis of \(10 \mathrm{H}\)-Indolo[3,2-b]quinoline (quindoline) is reported. The synthesis involved \(N\)-arylation of 3 -aminoquinoline with triphenylbismuth diacetate followed by oxidative cyclization using palladium(II) acetate. A selective \(N\)-alkylation methodolo