Efficient Synthesis of Enantiomerically Pure C2-Symmetric Diols via the Allylboration of Appropriate Dialdehydes
โ Scribed by P.Veeraraghavan Ramachandran; Guang-Ming Chen; Herbert C. Brown*
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 581 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
An enantioselective synthesis of C 2 -symmetric bis-homoallylic aromatic and heteroaromatic diamines in 54-89% yields, in 73-94% de and P98% ee has been achieved via the allylboration of the corresponding N,N 0 -bis(trimethylsilyl)dialdimines and N,N 0 -bis(diisobutylalumino)dialdimines with B-allyl
## Abstract For Abstract see ChemInform Abstract in Full Text.
The inter-and intramolecular coupling of imines promoted by samarium diiodide and Lewis acids or by Zn/MsOH was extensively studied. The intramolecular reaction of chiral, enantiomerically pure bis-imines was also considered, and allowed the efficient, stereoselective synthesis of 1,2-diamines with