A simple and low cost synthesis of d-ery
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Richard J.B.H.N. van den Berg; Cornelis G.N. Korevaar; Gijsbert A. van der Marel
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Article
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2002
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Elsevier Science
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French
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D-erythro-Sphingosine (1) and D-erythro -2-azidosphingosine (2) are both prepared from commercially available and cheap D-ribo -phytosphingosine (3) in a yield of 58% and 70%, respectively. A key transformation in the synthesis of D-erythro -sphingosine (1) is the palladium catalyzed regiospecific r