EFFICIENT SYNTHESIS OF CYTOTOXIC FURONAPHTHOQUINONE NATURAL PRODUCTS
β Scribed by Lee, Yong Rok; Kim, Byung So
- Book ID
- 126885105
- Publisher
- Taylor and Francis Group
- Year
- 2001
- Tongue
- English
- Weight
- 127 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0039-7911
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π SIMILAR VOLUMES
Diodantunezone was first isolated from Lantana achyrantifolia (Verbenaceae) and originally assigned as 8-hydroxy-4,9-dihydronaphtho[2,3-b]furan-4,9-diooe la but its structure was later revised to 5-hydroxy-4,9-dihydronaphthol2,3-b]furan-4,9-dione 2a. The regiospecific synthesis of diodantunezone 2a
The naturally-occuring furanonaphthoquinone le have been synthesized in good overall yield by a route involving directed ortho metalation (Scheme 1, 1 + 2).
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