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Efficient synthesis of apricoxib, CS-706, a selective cyclooxygenase-2 inhibitor, and evaluation of inhibition of prostaglandin E2 production in inflammatory breast cancer cells

✍ Scribed by Pijus K. Mandal; Eric M. Freiter; Allison L. Bagsby; Fredika M. Robertson; John S. McMurray

Book ID: 113496087
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 174 KB
Volume: 21
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2011.08.050

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## Abstract A highly efficient synthesis of the promising Cox‐2 inhibitor, apricoxib (VI), in only three steps from commercially available starting material is given.