𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Efficient Synthesis of an Enantiopure Thiasteroid by a Double Heck Reaction.

✍ Scribed by Lutz F. Tietze; Lars P. Luecke; Felix Major; Peter Mueller

Publisher
John Wiley and Sons
Year
2004
Weight
19 KB
Volume
35
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Stereoselective Synthesis of Novel 19-No
Stereoselective Synthesis of Novel 19-Nor-Steroids by a Double Heck Reaction
✍ LutzΒ F. Tietze; SΓΆnke Petersen πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 337 KB πŸ‘ 2 views

The estrane 4 was synthesized by two successive Heck reactions starting from enantiopure 2 and the cyclohexenone 5, which contains a (Z)-bromovinyl group. The first intermolecular Pd-catalyzed reaction leads to 10 in a highly regioand diastereoselective manner. Transformation of the enone [a] Georg-