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Efficient Synthesis of a Novel 4-Hydroxy-2,3-dioxocyclobut-1-enyl Group Containing Amino Acids

โœ Scribed by Shinada, Tetsuro; Hayashi, Ken-ichi; Hayashi, Toshihiro; Yoshida, Yasutaka; Horikawa, Manabu; Shimamoto, Keiko; Shigeri, Yasushi; Yumoto, Noboru; Ohfune, Yasufumi


Book ID
120154291
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
68 KB
Volume
1
Category
Article
ISSN
1523-7060

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โœ Ronald ten Have; Albert M van Leusen ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 487 KB

3-Nitroindoles (10) are prepared in good yields via a thermal 6n-electrocyclization of 2,3-(dialkenyl)-4-nitropyrroles (4) in nitrobenzene, a solvent which causes in situ aromatization of the initially formed dihydroindoles (8). The corresponding reaction of 2-alkenyl-3-alkadienyl-4-nitropyrroles (5