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Efficient synthesis of 3,4,5-trimethoxybenzaldehyde via Reissert aldehyde synthesis

✍ Scribed by Schwartz, Alan

Book ID
126863224
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
270 KB
Volume
47
Category
Article
ISSN
0022-3263

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## Abstract magnified image Reissert compounds 2 derived from isoquinoline, chloroformates and TMS‐cyanide were alkylated in position 1. The resulting alkylation products 3 as well as the precursors 2 reacted with Grignard reagents affording imidazoisoquinolines 4, 5, 7 and 8 by addition to the cy