𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Efficient synthesis of 2′,3′-dideoxynucleosides and 2′,3′-dideoxy C-nucleosides from D-glucosamine

✍ Scribed by Michael E. Jung; Ivan D. Trifunovich


Book ID
108381468
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
260 KB
Volume
33
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis and antiviral evaluation of α-
✍ Kohei Yamada; Hiroyuki Hayakawa; Shinji Sakata; Noriyuki Ashida; Yuichi Yoshimur 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 427 KB

We have identified a selective S(N)2' reaction triggered by iodide ion that leads to the ring-opening of 2,2'-anhydro-α-nucleosides. By applying the method, we have synthesized α-D-2',3'-didehydro-2',3'-dideoxy-3'-C-hydroxymethyl nucleosides, designed as potential antiviral agents.