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Efficient synthesis of 16–28 membered macrocyclic crown amides via ring closing metathesis

✍ Scribed by Yehia A Ibrahim; Haider Behbehani; Maher R Ibrahim; Rana N Malhas

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 224 KB
Volume: 59
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(03)01174-8

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✦ Synopsis

Ring closing metathesis of suitable diamides containing 1,v-dienes led to efficient synthetic approaches towards macrocylic polyoxadiamides 1 -18 with 16 -28 membered ring sizes in good to excellent yields using Grubbs' catalyst.

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