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Efficient Synthesis of 1,5-Benzodiazepines Mediated by Sulfamic Acid under Neat Condition or in Solution.

✍ Scribed by Zhenjiang Li; Yingjie Sun; Xinghua Ren; Weisi Li; Yuhu Shi; Pingkai Ouyang


Publisher
John Wiley and Sons
Year
2007
Weight
22 KB
Volume
38
Category
Article
ISSN
0931-7597

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Sulfamic acid: An efficient and green ca
✍ Min Xia; Yue-dong Lu πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 259 KB πŸ‘ 1 views

## Abstract It is described that sulfamic acid can be utilized as an effective and green catalyst for the synthesis of 1,5‐benzodiazepines in high yields from the solvent‐free condensation of o‐phenylenediamine (**1**) and ketones (**2**). Β© 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:354–358,