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Efficient Synthesis of 1,4,7-Triazacyclononane and 1,4,7-Triazacyclononane-Based Bifunctional Chelators for Bioconjugation

✍ Scribed by Désogère, Pauline; Rousselin, Yoann; Poty, Sophie; Bernhard, Claire; Goze, Christine; Boschetti, Frédéric; Denat, Franck


Book ID
126489775
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
662 KB
Volume
2014
Category
Article
ISSN
1434-193X

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The synthesis of chiral annulet 1,4,7-tr
✍ Gilles Argouarch; Colin L Gibson; Graham Stones; David C Sherrington 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 63 KB

Novel and flexible routes for the synthesis of chiral ring annulet 2,6-disubstituted 1,4,7-trimethyl-1,4,7-triazamacrocycles are described. Efficient macrocyclisations were realised provided that chiral analogues of N,N-bis-[2-(toluene-sulfonylamino)ethyl]-toluene-4-sulfonamide were used as the nucl