𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Efficient Syntheses of 2-Chloro-2‘-deoxyadenosine (Cladribine) from 2‘-Deoxyguanosine1

✍ Scribed by Janeba, Zlatko; Francom, Paula; Robins, Morris J.


Book ID
111653357
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
142 KB
Volume
68
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Protein binding of 2-chloro 2′-deoxyaden
✍ F. Albertioni; L. Herngren; G. Juliusson; J. Liliemark 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 202 KB

The plasma protein binding of 2-chloro-2'-deoxyadenosine (CdA) at 37°C was studied by ultrafiltration in 5 healthy volunteers, in 11 patients with haematological malignancies and in purified protein preparations. In the patients, the binding of CdA to plasma proteins was 25.0 % and in heaRhy subject

Lipid raft disruption prevents apoptosis
✍ Eriko Takahashi; Osamu Inanami; Toshio Ohta; Akira Matsuda; Mikinori Kuwabara 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 552 KB

To clarify the role of lipid rafts in 2-chloro-2'-deoxyadenosine (2CdA; Cladribine)-induced apoptosis, the effects of disruption of lipid rafts by methyl-beta-cyclodextrin (MbetaCD) and filipin on 2CdA-induced apoptosis were investigated in four human acute lymphoblastic leukemia (ALL) cell lines co