Efficient syntheses of 2-(2,6-dichloro-4
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Sanath K. Meegalla; Dario Doller; Ruiping Liu; Deyou Sha; Richard M. Soll; Dale
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Article
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2002
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Elsevier Science
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French
โ 259 KB
Two methods are described for the regiospecific synthesis of 3,4-fused-cycloalkyl-1-arylpyrazoles; the key step is the reaction between aryl hydrazines and cyclic a-(dimethoxymethyl)ketones. The latter are obtained by BF 3 -promoted alkylation of ketones with trimethylorthoformate.