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Efficient Sonogashira Coupling of Unprotected Halonucleosides in Aqueous Solvents Using Water-Soluble Palladium Catalysts

โœ Scribed by Joon Hyung Cho; Caitlin D. Prickett; Kevin H. Shaughnessy


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
196 KB
Volume
2010
Category
Article
ISSN
1434-193X

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โœ Axel Kรถllhofer; Herbert Plenio ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 182 KB ๐Ÿ‘ 2 views

## Abstract The Sonogashira coupling of various aryl bromides and iodides with different acetylenes was studied under biphasic conditions with soluble, polymerโ€modified catalysts to allow the efficient recycling of the homogeneous catalyst. For this purpose, several sterically demanding and electro