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Efficient selection of tagging single-nucleotide polymorphisms in multiple populations

✍ Scribed by Bryan N. Howie; Christopher S. Carlson; Mark J. Rieder; Deborah A. Nickerson


Book ID
106134377
Publisher
Springer
Year
2006
Tongue
English
Weight
439 KB
Volume
120
Category
Article
ISSN
0340-6717

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Single nucleotide polymorphisms (SNPs) play a central role in the identification of susceptibility genes for common diseases. Recent empirical studies on human genome have revealed block-like structures, and each block contains a set of haplotype tagging SNPs (htSNPs) that capture a large fraction o