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Efficient removal of loxP-flanked DNA sequences in a gene-targeted locus by transient expression of Cre recombinase in fertilized eggs

✍ Scribed by Shinji Sunaga; Kazushige Maki; Yoshinori Komagata; Koichi Ikuta; Jun-Ichi Miyazaki

Book ID: 111658897
Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 124 KB
Volume: 46
Category: Article
ISSN: 1040-452X
DOI: 10.1002/(sici)1098-2795(199702)46:2<109::aid-mrd1>3.0.co;2-u

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## Abstract Summary: Embryonic or neonatal lethality of mice with targeted disruption of critical genes preclude them from further characterization of specific roles of these genes during postnatal development and aging. In order to study the molecular roles of such genes in teeth, we generated tra