Facile reduction of aromatic nitro/azido
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Ahmed Kamal; K.Laxma Reddy; V. Devaiah; G.Suresh Kumar Reddy
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Article
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2003
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Elsevier Science
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French
β 355 KB
An efficient and mild method for the reduction of aromatic nitro and azido groups on solid support using Al/NiCl 2 β’6H 2 O and Al/NH 4 Cl is described. This solid phase reduction technique has been applied towards the synthesis of DNA binding pyrrolo[2,1-c][1,4]benzodiazepine antitumour antibiotics.