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Efficient recovery of recombinant human erythropoietin from milk of transgenic pigs by two-step pretreatment

✍ Scribed by Eun Gyo Lee; Seung Hui Lee; Kyoung Mi Park; Jung Eun Baek; Jin-Ki Park; Won-Kyong Chang; Joon-Ki Jung; Bong Hyun Chung

Book ID: 107637846
Publisher: The Korean Society for Biotechnology and Bioengineering
Year: 2008
Tongue: English
Weight: 298 KB
Volume: 13
Category: Article
ISSN: 1226-8372
DOI: 10.1007/s12257-007-0158-x

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## Abstract **BACKGROUND:** Human erythropoietin (hEPO), a hydrophobic acidic glycoprotein responsible for the regulation of red blood cell production in mammals, is used for the treatment of anemia. In general, the purification of transgenic animal‐derived therapeutic proteins is not easy due to t