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Efficient One-Pot, Two-Step, Microwave-Assisted Procedure for the Synthesis of Polysubstituted 2-Aminoimidazoles

✍ Scribed by Ermolat'ev, Denis S.; Babaev, Eugene V.; Van der Eycken, Erik V.


Book ID
117995680
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
83 KB
Volume
8
Category
Article
ISSN
1523-7060

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A one-pot combination of a modified FriedlΓ€nder annulation and a Knoevenagel condensation provides 2styrylquinolines in good to excellent yields. A variety of substrates are reacted in one-pot in the presence of 1-methylimidazolium trifluoroacetate ([Hmim]TFA).