Efficient one-pot synthesis of N-substituted phthalimides/naphthalimides from azides and anhydrides by iodotrimethylsilane
β Scribed by Ahmed Kamal; E. Laxman; N. Laxman; N. Venugopal Rao
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 117 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Substituted phthalimides and naphthalmlides have been obtained in good to excellent yields, employing chlorotrimethylsilane and sodium iodide (in sit. generation of iodotrimethylsilane) from corresponding azidcs and anhydrides under mild conditions.
π SIMILAR VOLUMES
## Abstract Starting with the __N__βsubstituted anilines 4/12 and the Ξ±βbranched ketones 3 the 3__H__βindolium salts 1 and their fused derivatives 13 are prepared by combining a sodium nitrite nitrosation, a zinc dust reduction, a hydrazone formation and a Fischer indolization to a reaction sequenc