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Efficient one-pot synthesis of mono and bis-N-cyclohexyl-3-alkyl(aryl)-quinoxaline-2-amines using N-halo catalysts

โœ Scribed by Ghorbani-Vaghei, Ramin; Amiri, Mostafa; Karimi-Nami, Rahman; Salimi, Zahra


Book ID
125452053
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
415 KB
Volume
3
Category
Article
ISSN
2046-2069

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An efficient one-pot synthesis of N-alky
โœ Ralph Nicholas Salvatore; Jeremy A Ledger; Kyung Woon Jung ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 127 KB

A facile one-pot synthesis of N-alkyl carbamates is described. A primary amine, CO 2 , and an alkyl halide underwent a three-component coupling using cesium carbonate and tetrabutylammonium iodide (TBAI) giving rise to the resultant carbamate. In the presence of Cs 2 CO 3 , subsequent N-alkylation o