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Efficient One-Pot Synthesis of 1-Aryl 1,2,3-Triazoles from Aryl Halides and Terminal Alkynes in the Presence of Sodium Azide.

✍ Scribed by Jacob Andersen; Simon Bolvig; Xifu Liang

Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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## Abstract The alkynes, CO and the aryl iodides undergo Pd‐catalyzed carbonylative Sonogashira reaction to yield an alkynone intermediate which is directly coupled with azide to give the title triazoles.