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Efficient one pot preparation of variously substituted thieno [2,3-b] thiophene

✍ Scribed by Alain Cornel; Gilbert Kirsch

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
47 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

An efficient one pot access to variously substituted thieno[2,3‐b]thiophene is described. The title compounds were obtained from 1,3‐dicarbonyl or equivalent compounds, carbon disulfide and halomethyl derivatives in good to high yields and fully characterized.

πŸ“œ SIMILAR VOLUMES

Synthesis of certain 5-substituted thien
Synthesis of certain 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and thieno[2,3-b]thiophene-2-sulfonamide 6,6-dioxides
✍ Hwang-Hsing Chen; Jesse A. May; Vincent M. Lynch πŸ“‚ Article πŸ“… 1999 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 669 KB

A series of the title compounds were prepared for evaluation as inhibitors of carbonic anhydrase II. Oxidation of 5-substituted thieno[2,3-b]thiophene-2-sulfonamides provided the first examples of thiophene[2,3-b]thiophene-2-sulfonamide 6,6-dioxides. These cyclic vinyl sulfones readily underwent add