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Efficient One-Pot 1,3-Dibromo-5,5-dimethylhydantoin (DBH)-Catalyzed Synthesis of Highly Substituted Furans

✍ Scribed by Hassan Ghasemnejad-Bosra; Mohammad Faraje; Setareh Habibzadeh


Book ID
102256860
Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
119 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

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The 1,3‐dibromo‐5,5‐dimethylhydantoin (DBH) was found to efficiently catalyze the one‐pot synthesis of highly functionalized tetrasubstituted furan derivatives by the reaction of 1,4‐diarylbut‐2‐ene‐1,4‐diones and acetoacetates in i‐PrOH as the solvent at 80–90Β° for 3–7β€…h. The products were formed in high yields (82–95%) under mild and neutral conditions.


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