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Efficient kinetic resolution of organosilicon compounds by stereoselective esterification with hydrolases in organic solvent

โœ Scribed by Akinori Uejima; Toshiaki Fukui; Eiichiro Fukusaki; Tetsuo Omata; Takuo Kawamoto; Kenji Sonomoto; Atsuo Tanaka


Publisher
Springer
Year
1993
Tongue
English
Weight
599 KB
Volume
38
Category
Article
ISSN
1432-0614

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Kinetic resolution of organosilicon comp
โœ Toshiaki Fukui; Min-Hua Zong; Takuo Kawamoto; Atsuo Tanaka ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 549 KB

Stereoselective dehydrogenation of three isomers of trimethylsilylpropanol was carried out with horse liver alcohol dehydrogenase (HLADH, EC 1.1.1.1.) and optically active organosilicon compounds were obtained in a water-organic solvent two-layer system with coenzyme regeneration. Furthermore, we ex