Efficient identification of tubby-bindin
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Nora B. Caberoy; Yixiong Zhou; Xiaoyu Jiang; Gabriela Alvarado; Wei Li
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Article
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2009
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John Wiley and Sons
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English
β 507 KB
## Abstract Mutation in the tubby gene causes adultβonset obesity, progressive retinal, and cochlear degeneration with unknown mechanism. In contrast, mutations in tubbyβlike protein 1 (Tulp1), whose Cβterminus is highly homologous to tubby, only lead to retinal degeneration. We speculate that thei