✦ LIBER ✦
Efficient heterocyclisation via 2-aza-cope rearrangements of α-acyliminium intermediates. Formation of pyrrolizidines and somel thia-analogues
✍ Scribed by Peter M.M. Nossin; Johannes A.M. Hamersma; W.Nico Speckamp
- Book ID
- 104221155
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 227 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
HCmH-ring closures of OH-lactams 7 possessing an ally1 substituted alkene function solely afford pyrrolizidines 8 and-2 in high yield via 2-aza-Cope rearrangent and ensuing cl-acyliminium cyclisation.