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Efficient gene transfer and targeted mutagenesis in Fusobacterium nucleatum

✍ Scribed by Susan Kinder Haake; Sean Yoder; Sharon Hunt Gerardo


Book ID
113855238
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
266 KB
Volume
55
Category
Article
ISSN
0147-619X

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## Abstract To generate temporally controlled targeted somatic mutations selectively and efficiently in hepatocytes, we established SA^+/CreERT2^ mice in which the tamoxifen‐dependent Cre‐ER^T2^ recombinase coding sequence preceded by an internal ribosomal entry site was inserted in the 3β€² untransl