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Efficient Gene Therapy for Parkinson's Disease Using Astrocytes as Hosts for Localized Neurotrophic Factor Delivery

✍ Scribed by Drinkut, Anja; Tereshchenko, Yuliya; Schulz, Jörg B; Bähr, Mathias; Kügler, Sebastian


Book ID
124093723
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
960 KB
Volume
20
Category
Article
ISSN
1525-0016

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Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects approximately 1,000,000 Americans. The cause of the disease remains unknown. The histopathological hallmarks of the disease are dopaminergic striatal insufficiency secondary to a loss of dopaminergic neurons in the sub