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Efficient Differentiation of Mouse Embryonic Stem Cells into Motor Neurons

✍ Scribed by Wu, Chia-Yen; Whye, Dosh; Mason, Robert W.; Wang, Wenlan

Book ID
120015185
Publisher
MyJoVE Corporation
Year
2012
Tongue
English
Weight
496 KB
Volume
64
Category
Article
ISSN
1940-087X

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## Abstract Embryonic stem (ES) cells have the capacity to differentiate into endodermal, mesodermal, and ectodermal lineages. Motor neuron (MN) differentiation of mouse ES cells involves embryoid bodies formation with addition of Sonic hedgehog and retinoic acid. In this work, using immunocytochem