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Efficient diastereoselective synthesis of anti-α-bromo-β-hydroxyketones

✍ Scribed by Herbert C. Brown; Mu-Fa Zou; P.Veeraraghavan Ramachandran

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
143 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

anti-ot-Bromo-~3-hydroxyketones were synthesized in high diastereoselectivity via the enolboration of a representative series of bromomethylketones using dicyclohexylboron chloride, followed by aldolization with aldehydes.

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