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Efficient Darzens condensation reactions of aromatic aldehydes catalyzed by polystyrene-supported phase-transfer catalyst

โœ Scribed by Zongting Wang; Liwen Xu; Zonggang Mu; Chungu Xia; Hanqing Wang


Book ID
108211331
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
73 KB
Volume
218
Category
Article
ISSN
1381-1169

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Diastereoselective Darzens reactions of
โœ Shigeru Arai; Yukari Suzuki; Kazuyuki Tokumaru; Takayuki Shioiri ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 87 KB

The development of the highly diastereoselective catalytic synthesis of glycidic acid derivatives via Darzens reaction is described. The reaction of a-chloroesters and amides with aromatic aldehydes smoothly proceeds in the presence of a quaternary ammonium salt as a phase-transfer catalyst to give