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Efficient Biginelli Reaction Catalyzed by Sulfamic Acid or Silica Sulfuric Acid under Solvent‐Free Conditions

✍ Scribed by Chen, Wei‐Yi; Qin, Su‐Dong; Jin, Jian‐Rong


Book ID
120379772
Publisher
Taylor and Francis Group
Year
2007
Tongue
English
Weight
85 KB
Volume
37
Category
Article
ISSN
0039-7911

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An efficient and clean method was developed for the one-pot synthesis of pyrimidinones by ytterbium chloride catalyzed Biginelli-type reaction of aromatic aldehyde, cyclopentanone, and urea or thiourea under solvent-free conditions.