Efficient assembly of recombinant major histocompatibility complex class I molecules with preformed disulfide bonds
✍ Scribed by Lars Østergaard Pedersen; Mogens Holst Nissen; Nils Jakob Vest Hansen; Lise Lotte Nielsen; Sanne Lise Lauenmøller; Thomas Blicher; Anneline Nansen; Christina Sylvester-Hvid; Allan Randrup Thromsen; Søren Buus
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 227 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0014-2980
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📜 SIMILAR VOLUMES
With P,-microglobulin-( P2m-) cell lines such as RIE/Db, the surface expression of class I major histocompatibility complex molecules is greatly impaired, and class I molecules that are on the surface are generally misfolded. To determine whether P2m must be continually present with the class I heav
## Abstract Surface expression of the majority of class I major histocompatibility complex (MHC) heavy chains is known to require assembly with β~2~ microglobulin (β~2~m). To define other factors involved in class I MHC assembly, we have studied two tumor cell lines that are deficient in cell surfa