Efficient Assembly of an Indole Alkaloid Skeleton by Cyclopropanation: Concise Total Synthesis of (±)-Minfiensine

✍ Scribed by Liqun Shen; Min Zhang; Yi Wu; Yong Qin

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 326 KB
• Volume: 47
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200800566

✦ Synopsis

Members of the akuammiline [1] alkaloids such as echitamine, [2] vincorine, [3] and corymine, [4] like indole alkaloid minfiensine, [5] possess a highly congested pentacyclic ring system (Figure 1). These alkaloids exhibit a number of