Efficient and stereoselective synthesis of (2S,3S,4S)-3,4-dihydroxyglutamic acid via intramolecular epoxidation
β Scribed by Hyeonjeong Kim; Dongwon Yoo; Soo Young Choi; Young Keun Chung; Young Gyu Kim
- Book ID
- 108284371
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 263 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0957-4166
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A catalytic deuteration of protected 3,4-dehydro-L-proline using RuCI2(PPh3) 3 followed by RuO~-oxidation gave a 3,4-dideuterated L-pyroglutamic acid derivative which is considered to be a promising precursor for various deuterated amino acids. The present study demonstrates a stereoselective reduct