Efficient algorithms for identifying orthologous simple sequence repeats of disease genes
β Scribed by Chienming Chen; Chihchia Chen; Tsanhuang Shih; Tunwen Pai; Chinhua Hu; Wenshyong Tzou
- Publisher
- Academy of Mathematics and Systems Science, Chinese Academy of Sciences
- Year
- 2010
- Tongue
- English
- Weight
- 155 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1009-6124
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## Communicated by Michael Dean Simple sequence repeats (SSRs) have traditionally been used as markers in gene mapping studies and typing for forensic purposes. Recently there has been some speculation that this type of genetic variation also plays a more direct role in influencing gene expression
In the segment-based approach to sequence alignment. nucleic acid, and protein sequence alignments are constructed from fragments, i.e., from pairs of ungapped segments of the input sequences. Given a set F of candidate fragments and a weighting function w : F + FL:, the score of an alignment is de