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Efficiency of utilization of thymine and 5-bromouracil for normal and repair DNA synthesis in bacteria

✍ Scribed by Lee Kanner; Philip Hanawalt

Book ID
115743025
Publisher
Elsevier Science
Year
1968
Weight
796 KB
Volume
157
Category
Article
ISSN
0005-2787

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Escherichia coli mutants defective in DNA uracil N-glycosidase (ung-) or endonuclease VI active against apurinic/apyrimidinic sites in DNA (xthA-) exhibit enhanced sensitivity towards 5-bromodeoxyuridine relative to the wild type strain, pointing to involvement of these enzymes in repair of bromoura